UK Life Sciences Company Directory

Targeting mitochondrial dysfunction in neurodegeneration

NRG Therapeutics is a clinical-stage neuroscience company developing small molecule inhibitors of the mitochondrial permeability transition pore as disease-modifying treatments for neurodegenerative disorders. Its lead candidate, NRG5051, entered Phase 1 clinical trials in January 2026 for ALS and Parkinson's disease.…

Contract microbial whole genome sequencing and metagenomics service

MicrobesNG Ltd is a UK-based contract sequencing service provider specialising in microbial whole genome and metagenome sequencing. The company processes bacterial, fungal, and viral samples using Illumina short-read and Oxford Nanopore long-read platforms, with DNA extraction and bioinformatics analysis included as…

Chemical structure software and cheminformatics platforms

Chemaxon is a cheminformatics software company developing tools for chemical structure drawing, molecular property prediction, structure searching and compound registration. Its technologies support medicinal chemistry, molecular design and chemical data management across pharmaceutical, biotechnology and other…

Carbon nanodot delivery platform for RNA-based crop protection

CDotBio Limited is a biotech developing carbon nanodot technology to improve the delivery and stability of RNA-based biopesticides and other crop inputs. The platform uses ultra-small, sugar-derived nanoparticles to protect RNA cargo from degradation as it transits into plant cells, enabling species-specific targeting…

Biomarker-guided therapeutics for psychosis-related cognitive impairment

Monument Therapeutics is a clinical-stage biopharmaceutical company developing stratified treatments for neuropsychiatric conditions. Its lead programme, MT1988, is being evaluated in people at clinical high risk of psychosis. A randomised, placebo-controlled Phase 1/2 study dosed its first participant in March 2026…

Enzymatic DNA synthesis for pharmaceutical and biotechnology research

Camena Bioscience is a synthetic biology company that develops and supplies enzymatic gene synthesis technology to pharmaceutical and biotechnology customers. Its multi-enzymatic approach to DNA synthesis offers substantially improved accuracy and access to longer, more complex sequences compared to conventional…

GCP-accredited oncology molecular diagnostics for clinical trials and research

The Cancer Molecular Diagnostics Laboratory is an ISO 15189-accredited molecular diagnostics facility within the University of Cambridge Department of Oncology, jointly funded by CRUK and NIHR. Operating to GCP and GCLP standards, it provides next-generation sequencing, circulating tumour DNA analysis, liquid biopsy…

Oligonucleotide therapeutics designed to upregulate protein expression

Orfonyx Bio is a biotechnology company developing genetic medicines that increase, rather than silence, the expression of therapeutic target proteins. Its platform generates antisense oligonucleotide modulators that act on regulatory elements within the untranslated regions of genes, inhibiting sequence motifs that…

Clinical-stage biopharma developing treatments for cancer and rare diseases

Biodexa Pharmaceuticals is a Cardiff-based clinical-stage biopharmaceutical company advancing a pipeline of proprietary drug formulations for diseases with high unmet need. Its lead programme, eRapa, an encapsulated oral formulation of rapamycin, is in a Phase 3 registrational trial for familial adenomatous polyposis,…

IVD manufacturer serving clinical laboratory and transfusion medicine

QuidelOrtho is a global in vitro diagnostics company with a major UK manufacturing and development facility in Pencoed, Wales, employing over 600 people. The site produces immunohematology reagents for transfusion medicine and immunoassay products covering infectious disease, endocrinology, and oncology testing,…

Microbial crop inoculants for nitrogen fixation and soil health

Legume Technology is an agricultural biotechnology company manufacturing microbial inoculants that support crop establishment and nutrient uptake. Its formulations contain nitrogen-fixing Rhizobium bacteria, mycorrhizal fungi and Bacillus species, tailored to legumes and other crops. These living products are applied…

Molecular modelling and cheminformatics software for drug discovery

Chemical Computing Group is a scientific software company developing molecular modelling and cheminformatics tools for drug discovery. Its flagship software supports structure-based design, molecular docking, pharmacophore screening and simulations involving small molecules, peptides and proteins. Researchers use…

Pathogen genomic surveillance tools and antimicrobial resistance research

Centre for Genomic Pathogen Surveillance is a University of Oxford research centre developing genomic epidemiology methods and tools for infectious disease surveillance. Its Pathogenwatch and Microreact platforms support pathogen genome analysis, antimicrobial resistance prediction, strain clustering and visualisation…

Point-of-care HPV self-testing for cervical cancer screening

10zyme is an early-stage medical technology company developing a point-of-care self-test for high-risk human papillomavirus, integrating synthetic biology with machine learning to deliver instant results without laboratory processing. Its test screens for all 14 high-risk HPV types linked to cervical cancer,…

Agri-tech sensors, machine learning and gene editing for fresh produce

B-Hive Innovations is an agri-tech research and development company that designs sensor systems, machine learning tools, and hardware solutions for the fresh produce industry. Working with farmers, packers, and supply chain partners, the company addresses challenges including non-destructive crop quality assessment,…

Contract analytical chemistry and quality control testing for pharmaceutical materials

Butterworth Laboratories is an independent contract analytical chemistry laboratory providing quality control testing, method development and stability testing to the pharmaceutical and related industries. The company tests raw materials, excipients, active pharmaceutical ingredients and finished products against…

XF-73 antimicrobial advancing towards Phase 3 infection prevention

AMR Bio is a clinical-stage biotechnology company developing the XF-73 antimicrobial platform for preventing hospital-acquired infections. Its lead nasal formulation aims to reduce Staphylococcus aureus carriage before surgery. Following Phase 2b clinical testing, the programme is preparing for Phase 3 development.…

Engineering biology research for pollution removal and resource recovery

Environmental Biotechnology Innovation Centre is a Cranfield University-led research partnership applying engineering biology to environmental monitoring, pollution removal and resource recovery. Its programme develops engineered microorganisms, enzymes, biofilms and biosensors for challenges including PFAS…

AI-driven natural product discovery for neurological therapeutics

Pangea Bio is a clinical-stage biotechnology company developing small molecule therapeutics for neurological and neuropsychiatric disorders. Its proprietary AI platform screens natural and plant-derived chemical space, integrating ethnobotanical data with machine learning to identify novel CNS drug candidates with…

CreaTap antibody engineering for improved solid tumour penetration

Creasallis is a biotechnology company developing antibody engineering technologies intended to improve drug delivery into solid tumours. Its patented CreaTap platform modifies therapeutic antibodies to promote deeper penetration into tumour tissue. The approach is under development for monoclonal antibodies,…