UK Life Sciences Company Directory

Oral NLRP3 inhibitors for cardiovascular and neurologic inflammation

Rezera, formerly NodThera, is a clinical-stage biotechnology company developing small molecule inhibitors of NLRP3, an inflammasome implicated in chronic inflammatory and neurodegenerative disease. Its lead asset, ruvonoflast, is a brain-penetrant oral inhibitor that has completed Phase II trials and is advancing…

Sterile GMP fill/finish CMO for biologics and small molecules

Symbiosis Pharmaceutical Services is a contract manufacturing organisation specialising in sterile GMP fill/finish manufacturing of injectable drug products for clinical trials and low-volume commercial supply. Operating from a purpose-built MHRA-licensed and FDA-inspected facility in Stirling, the company handles a…

Circadian hormone therapeutics for rare endocrine conditions

Neurocrine UK is the European operations of Neurocrine Biosciences, a Cardiff-headquartered specialty pharmaceutical company developing and commercialising hormone therapeutics for rare and chronic endocrine conditions. The company's scientific approach centres on circadian-based formulation technology, designed to…

Specialist molecular pathology, histopathology and spatial biology CRO

Propath (UK) is a contract research organisation providing GLP and GCP-compliant molecular pathology, histopathology, and spatial biology services to the global biopharmaceutical industry. Operating from a dedicated 12,000 square foot facility in Hereford, the company delivers spatial transcriptomics, highly…

Lentiviral vector platform improving yield for advanced cell therapies

Lentitek is a biotechnology company developing proprietary lentiviral vector manufacturing technology for cell and gene therapy developers. Its platform uses novel promoter engineering to reduce unwanted payload gene expression in manufacturing cell lines, improving vector yield, quality and potency. The technology…

Custom radiolabelling and integrated small molecule drug discovery services

Eurofins Selcia is a contract research organisation specialising in custom carbon-14 and stable isotope radiolabelling, GMP radiolabelled API manufacturing, and integrated small molecule drug discovery. Its radiochemistry services support preclinical and clinical ADME studies, human mass balance trials, dermal…

Full-service CRO for Phase I–IV pharmaceutical and device trials

Clinicology is a contract research organisation providing clinical trial management services to pharmaceutical, biotechnology, and medical device companies. Services span site startup, monitoring, project management, regulatory submissions, patient recruitment, medical monitoring, medical writing, and…

Metagenomic microbiome analysis for aquaculture health monitoring

Esox Biologics is a biotechnology company providing metagenomic analysis for aquaculture health monitoring. Its Detect service sequences microbial DNA in water and animal swab samples, profiling pathogens and beneficial microorganisms without predefined target panels. The company also researches bacteriophage-based…

Non-invasive skin epigenomics platform for clinical and cosmetic research

Mitra Bio is a contract research organisation providing a non-invasive skin epigenomics platform to pharmaceutical and cosmetic companies conducting clinical trials on dermatological and age-reversal interventions. Using tape-strip skin sampling combined with whole-genome DNA methylation sequencing and bioinformatic…

Engineered T-regulatory cell therapies for immune-mediated diseases

Quell Therapeutics is a clinical-stage UK biotech developing engineered T-regulatory (Treg) cell therapies for immune-mediated diseases, using its proprietary technology to engineer Tregs with enhanced persistence and potency. Its lead candidate QEL-001 is in the Phase 1/2 LIBERATE trial for liver transplant…

Amniotic membrane biotherapies for ocular surface repair and regeneration

NuVision Biotherapies is a regenerative medicine company developing tissue-based biotherapies for ocular surface disease and trauma. Its proprietary processing technology manufactures dry-preserved human amniotic membrane grafts that retain the membrane's natural barrier and healing properties whilst enabling ambient…

Microalgae-based omega-3 producer using whisky co-products

MiAlgae is a company that grows omega-3-rich microalgae by upcycling nutrient-rich co-products from whisky distillation, offering a fish-free alternative to fishmeal for aquaculture, pet food, and animal feed markets. Operating 30,000-litre bioreactors at its demonstrator site in Balfron, Stirlingshire, the company is…

Precision fermentation platform producing animal-free dairy proteins

Better Dairy is a biotechnology company using precision fermentation to produce animal-free dairy proteins including casein and osteopontin. By engineering yeast to express mammalian milk proteins, the company produces bioidentical ingredients that enable food manufacturers to make dairy products without livestock.…

Synthetic chemical receptor R&D for implantable glucose biosensors

Lifecare Chemistry Ltd is a UK R&D subsidiary of Norwegian medical sensor company Lifecare ASA, established to develop and own proprietary analyte-specific synthetic receptors for use in Lifecare's implantable continuous glucose monitoring technology. Working in collaboration with researchers at the University of…

Specialist pharmacovigilance and drug safety services globally

PrimeVigilance is a contract research organisation specialising in pharmacovigilance and medical information services for pharmaceutical, biotechnology and medical device companies. The company delivers clinical safety monitoring, post-marketing surveillance, signal detection, benefit-risk management, literature…

TYK2/JAK1 inhibitor advancing towards Phase 2 psoriasis trials

Sareum is a clinical-stage biotechnology company developing small-molecule kinase inhibitors for autoimmune diseases and cancer. Its lead oral TYK2/JAK1 inhibitor, SDC-1801, completed Phase 1 testing in healthy volunteers and is being prepared for a Phase 2 study in psoriasis. Dosing in its Phase 2-enabling toxicology…

AI-driven enzyme discovery for sustainable industrial ingredients

Scindo is a UK biotechnology company developing an AI-powered enzyme discovery and engineering platform to produce bio-based alternatives to petroleum-derived industrial ingredients. The company combines machine learning with proprietary experimentally validated reaction datasets to discover and optimise enzymes…

AI-assisted imaging software for minimally invasive vascular surgery

Cydar Medical is a medical software company developing AI-assisted imaging tools for minimally invasive vascular surgery. Its cloud-based platform creates three-dimensional anatomical maps from CT scans and overlays them on live X-ray images to support procedural planning and intraoperative navigation. The software…

Rejuvenation biology company decoding the genomics of cellular ageing reversal

clock.health is a biotechnology company developing therapies to reverse cellular ageing and extend healthspan by decoding the biological programmes that govern cell rejuvenation. Using a proprietary model in which human induced pluripotent stem cells are artificially aged then permitted to self-rejuvenate, the company…

Immunometabolism-targeting small molecules for autoimmune disease

Sitryx Therapeutics is a clinical-stage biopharmaceutical company developing oral small molecule therapeutics that modulate immune cell metabolism to achieve disease remission in autoimmune and inflammatory conditions. The company's approach targets novel metabolic enzymes within immune cells, with lead programmes in…