UK Life Sciences Company Directory

Systemic viral immunotherapy for solid tumours

Stratosvir develops engineered viral immunotherapies for advanced solid tumours and their metastases. Its platform aims to overcome the limitations of injecting therapeutic viruses directly into tumours by enabling systemic, intravenous delivery. Within tumour tissue, the viruses are designed to replicate selectively…

Blood-based microRNA test for multi-cancer early detection

Xgenera is a diagnostics company developing a blood test for the early detection of multiple cancers from a single sample. The test measures circulating microRNA biomarkers using PCR-based methods and applies machine learning to identify signals from up to 12 common cancers before symptoms appear. The company is…

Synthetic promoter platform for precision gene expression control

Chromatin Bioscience designs synthetic promoters and gene expression control systems for cell and gene therapy developers. Its platform uses bioinformatics to identify cell-type-selective regulatory elements from the human genome, which are assembled into novel synthetic promoters enabling precise, durable and…

Antibodies, proteins and immunoassays for life science research

Proteintech Europe is the UK and European subsidiary of Proteintech Group, a US-based manufacturer of research reagents. The company produces antibodies, recombinant proteins, nanobodies and immunoassay kits for life science research, with a catalogue covering more than 13,000 protein targets. Additional product lines…

Contactless respiratory monitoring and digital biomarkers for clinical trials

Albus Health is a clinical research technology company developing passive, contactless monitoring for respiratory studies and pharmaceutical trials. Its bedside Albus Home system combines acoustic and other sensors to measure nocturnal cough, breathing and environmental conditions without requiring patients to wear…

Capacitance-based biomass monitoring instruments for bioprocessing and brewing

Aber Instruments develops and manufactures online probes and instrumentation for real-time viable cell monitoring in bioprocessing and brewing applications. The company's capacitance-based technology measures live cell concentration in fermenters and bioreactors across yeast, bacterial, animal, insect and plant cell…

Perfluorocarbon oxygen carrier therapeutic and MRI imaging agent for acute stroke

Aurum Biosciences is a Scottish clinical-stage biopharmaceutical company developing ABL-101, a perfluorocarbon-based oxygen carrier that bypasses arterial clots to deliver oxygen to ischaemic tissue via collateral vessels. The lead indication is acute ischaemic stroke, with ABL-101 having completed Phase 1 and 2a…

Multimodal engineered T-cell therapies for treatment-refractory solid cancers

Alceus Bio is a biotechnology company developing next-generation engineered T-cell therapies for solid tumours. Its platform uses generative AI and synthetic biology to design therapeutic proteins that patient-derived immune cells are programmed to express and deliver in situ, targeting intracellular disease drivers…

Bacterial bioinoculant replacing synthetic nitrogen fertiliser in crops

NetZeroNitrogen is a biotechnology company developing a biological alternative to synthetic nitrogen fertiliser based on a naturally occurring endophytic bacterium that fixes atmospheric nitrogen within plant cells. The technology is designed to reduce dependence on synthetic nitrogen inputs, lowering associated…

AI bioprocess simulation and downstream manufacturing optimisation software

New Wave Biotech is a software company developing AI-powered tools for bioprocess simulation and downstream manufacturing optimisation. Its Bioprocess Foresight platform combines mechanistic process models with machine learning to predict product yield, process costs and environmental impacts. Scientists and engineers…

Compostable polymer materials produced through microbial fermentation

Shellworks is a materials biotechnology company that develops and manufactures a bio-based, home-compostable polymer produced through microbial fermentation of plant-derived waste feedstocks. The polymer is formulated to replicate the functional properties of conventional plastic while biodegrading fully in home…

AstraZeneca's rare disease arm targeting the complement cascade

Alexion, AstraZeneca Rare Disease is the rare disease group within AstraZeneca, formed following the 2021 acquisition of Alexion Pharmaceuticals. With nearly 30 years of rare disease heritage, the division focuses on novel molecules targeting the complement cascade across haematology, nephrology, neurology, metabolic…

ML-guided strain engineering to optimise precision fermentation yields

Eden Genetics is a biotechnology company using machine learning to improve recombinant protein production through microbial strain engineering. Its computational platform analyses genetic and fermentation data to identify modifications intended to increase protein secretion and productivity in precision-fermentation…

Plant-based molecular farming platform for bio-identical collagen production

LeafyColl is a biotech developing a molecular farming platform for the scalable, plant-based production of bio-identical human collagen and other specialty proteins. The system uses engineered plants as programmable bio-factories to produce high-purity collagen for applications spanning regenerative medicine, wound…

Selective gluten-degrading enzymes for wheat-based food production

Prozymi Biolabs is an Edinburgh biotechnology company developing enzymes that selectively degrade immunogenic gluten peptides in wheat-based foods. Its technology aims to reduce sequences associated with coeliac immune responses while retaining the gluten functionality needed for bread texture. It targets conventional…

Prospective human biosample collection for translational research

The Sample Network is a clinical research services company arranging human biosample collection for biomarker, diagnostic and therapeutic development. It works with a network of clinical sites to design prospective collection studies tailored to sample type, patient characteristics, processing protocols and associated…

Formulation development CDMO for difficult pharmaceuticals

Agility Life Sciences is a contract development and manufacturing organisation specialising in pharmaceutical formulation development. Based in Stapleford, Nottingham, the company helps biotech and pharma clients overcome solubility, stability, and bioavailability challenges across oral, ocular, intravenous,…

Integrated drug discovery CRO from target to clinical candidate

Sygnature Discovery is a UK-headquartered integrated drug discovery contract research organisation. Operating from sites in Nottingham, Alderley Park, and Glasgow, the company provides end-to-end drug discovery services spanning target identification, medicinal chemistry, in vitro bioscience, structural biology,…

In vitro respiratory and inhalation toxicology testing services

ImmuONE is a contract research company specialising in in vitro inhalation toxicology and respiratory safety assessment. The company develops and applies human alveolar macrophage and epithelial cell culture models to evaluate the safety and efficacy of inhaled compounds, providing an alternative to animal testing.…

UK manufacturer of autoclaves and sterilizers for laboratory and pharma

Astell Scientific is a UK manufacturer of laboratory, pharmaceutical, and hospital autoclaves, steam sterilizers, steam generators, and thermal effluent decontamination systems. Its PLC-controlled autoclave range spans benchtop and floor-standing configurations designed for laboratory, GMP pharmaceutical…