UK Life Sciences Company Directory

Structural chemistry database and software for drug discovery

The Cambridge Crystallographic Data Centre (CCDC) is a non-profit organisation that curates and distributes the Cambridge Structural Database (CSD), the world's repository of experimentally determined small-molecule organic and metal-organic crystal structures, containing over one million entries. Alongside the…

Microbially produced leather alternative for luxury fashion

Replica Biomaterials is an industrial biotechnology company developing sustainable leather alternatives using engineered microbes. Its fermentation-based platform grows microbial biomaterials that are animal-free and petrochemical-free, with built-in customisable colour, eliminating the tanning and dyeing processes…

Reagents that stabilise and fix RNA, DNA and tissue samples

RNAssist is a reagents company developing patented stabilisation and fixation products for biological samples. Its formulations, based on deep eutectic solvents, preserve RNA, DNA, proteins and cell structure at the point of collection and are compatible with downstream methods such as single-cell sequencing and…

Contract isolation and purification of high-value compounds using HPCCC

BioExtractions Wales is a contract extraction and purification company operating from a 10,000 sq ft facility in Tredegar, South Wales. The company provides isolation and purification services to the pharmaceutical, agrochemical, chemical, and food industries using High Performance Counter Current Chromatography,…

Connected lab software and cell culture automation technology

Cell Culture Automation is a laboratory technology company developing software and instruments for cell culture research. Its live management platform integrates electronic notebooks, sample and inventory tracking, experimental records, equipment monitoring and budgeting. A plate-format environmental sensor monitors…

AI analysis of brain MRI for neurological diagnosis and prognosis

Ainostics is a medical artificial intelligence company developing software that analyses brain scans and clinical data to support the diagnosis and prognosis of neurological disorders. Its platform derives detailed measures of brain tissue structure from routine MRI and compares them with healthy populations to detect…

Single-molecule counting point-of-care diagnostics for cardiac and other biomarkers

Psyros Diagnostics develops a point-of-care diagnostic system using single-molecule counting technology to measure biomarkers at extremely low concentrations within around ten minutes, from a single drop of blood. The platform's lead application is a high-sensitivity troponin assay for cardiac diagnosis, with the…

Research kits and services for RNA-binding protein analysis

Ascent RNA is an early-stage biotechnology company developing molecular biology tools and research services for analysing RNA and its interactions with proteins. Its proprietary methods are designed to help researchers identify RNA targets and characterise RNA-binding proteins, with planned laboratory kits and…

Gene editing tools, cell lines and genomic reagents for life science research

Horizon Discovery is a Cambridge-based life sciences company supplying gene editing and gene modulation tools, services, and engineered cell lines to pharmaceutical, biotechnology, and academic customers. Its portfolio includes CRISPR and RNAi reagents, isogenic cell line pairs modelling disease-associated mutations,…

European specialty pharma focused on gastroenterology and hepatology

Norgine is a European specialty pharmaceutical company developing, manufacturing, and commercialising medicines across gastroenterology, hepatology, and cancer supportive care. Founded in 1906 and privately owned, the company markets a portfolio of specialty pharmaceutical products and medical devices across Europe,…

AAV gene therapies for rare and neurological diseases

Spur Therapeutics is a clinical-stage biotechnology company developing adeno-associated virus-based gene therapies for serious chronic diseases. Its lead programme is a Phase I/II gene therapy for Gaucher disease type 1, a rare lysosomal storage disorder. Further pipeline candidates target GBA1 Parkinson's disease and…

Portable semen quality analyser for livestock fertility assessment

Dyneval is a Scottish biotechnology company that developed the UK's only portable instrument for measuring livestock semen quality. The technology quantifies sperm motility lifetime under quasi-physiological conditions, providing vets and genetics companies with on-site data to inform breeding decisions and reduce…

Enzyme indicator technology for hydrogen peroxide bio-decontamination

Protak Scientific manufactures Enzyme Indicator technology, a rapid validation tool for measuring hydrogen peroxide gaseous bio-decontamination efficacy in pharmaceutical manufacturing and cleanroom environments. Developed in collaboration with Public Health England, the system delivers results in 60 seconds and is…

Liquid biopsy NGS kits and genomic diagnostic services

Nonacus is a developer of next-generation sequencing reagents and library preparation kits for liquid biopsy and tissue-based genomic analysis. Its target enrichment and cell-free DNA workflow products support cancer detection, treatment stratification, and longitudinal monitoring. Through its clinical services…

Engineering biology CRDMO for pharma and industrial biotech

Ingenza is a contract research, development, and manufacturing organisation applying engineering biology to solve manufacturing challenges across pharmaceuticals and industrial biotechnology. The company provides strain and cell line engineering, fermentation, bioprocess development, and analytical services for…

Affordable biochemicals, antibodies and reagents for life science research

Hello Bio is a Bristol-based manufacturer and supplier of biochemicals, antibodies, and reagents for life science research, offering validated tools at up to half the price of major suppliers. Products are manufactured in-house under ISO 9001 certification and span receptor ligands, enzyme inhibitors, ion channel…

Fragment-based drug discovery platform for oncology and CNS disorders

Astex Pharmaceuticals is a drug discovery and development company pioneering fragment-based drug discovery through its proprietary Pyramid platform, applied to oncology and central nervous system disorders. Astex maintains an internal pipeline alongside active collaborations with MSD targeting KRAS and p53. The…

Blood-based circulating tumour DNA tests for cancer

Inivata is a liquid biopsy company developing molecular tests for cancer using circulating tumour DNA from blood samples. Its sequencing-based assays identify tumour-associated genetic changes and have been used to investigate residual disease, recurrence and treatment response. The technology supports molecular…

AI-designed extended-expression RNA therapeutics for cardio-metabolic disease

ScionxBio, formerly Eleven Therapeutics, is a biotechnology company developing xRNA, a chemically expanded RNA modality engineered to extend protein expression from days to months. Combinatorial chemistry and deep learning are combined to design molecules with enhanced stability and reduced immune sensing, enabling…

University core facility for spatial transcriptomics and multi-omics

The Spatial Biology Facility is a university core research facility offering spatial transcriptomics, proteomics and multi-omics services. Using imaging-based platforms, it maps RNA and protein expression at single-cell resolution within intact tissue sections. The facility supports researchers with experimental…