Cell line development companies create and optimise cell lines for research, drug discovery and the manufacture of biological products. Their services support the production of recombinant proteins, antibodies, vaccines and advanced therapies.
This category includes companies working on:
Browse 62 UK cell line development companies below.
Label-free single-cell analysis platform for bioprocess monitoring
Cytomos is a biotechnology company developing label-free single-cell analysis instruments for the biopharmaceutical industry. Its platform uses dielectric spectroscopy and proprietary silicon chip sensors to generate unique cellular fingerprints based on intrinsic cell properties, without requiring labels or markers.…
Programmable RNA for scalable cell engineering and biomanufacturing
Plurify is a biotechnology company developing PluRNA, a programmable RNA platform for sustained protein expression without genome integration. Its technology is designed to engineer cells through controllable RNA-based programmes, with applications in stem-cell therapy manufacturing, cell purification, biologics…
Integrated bioprocessing technologies, consumables and services for biopharma
Sartorius Stedim Biotech is a global supplier of bioprocessing technologies, filtration systems, single-use solutions and laboratory instruments for the biopharmaceutical industry. Its UK operations span manufacturing, commercial and contract testing functions, including sites in Stonehouse (consumables and single-use…
Cell culture CDMO for cultivated meat and sustainable food biotech
Extracellular is a Bristol-based contract development and manufacturing organisation supporting companies developing cell-cultured food, cosmetic, and materials products. The company provides process development, scale-up, and biomanufacturing services for cultivated meat and other animal and plant cell culture…
UK national innovation centre for cell and gene therapy
Cell and Gene Therapy Catapult is a UK independent innovation organisation established to advance the cell and gene therapy industry by bridging the gap between research and commercial scale. It operates GMP-compliant Manufacturing Innovation Centres in Stevenage and Braintree, offering process development, technology…
CRISPR genome editing and engineered cell models for research
Prime.io is a contract research organisation providing genome editing services and reagents for drug discovery and functional genomics. Its work includes CRISPR knock-in and knock-out cell line generation, gene editing design, pooled screening and sequencing-based validation. The company develops engineered cellular…
3D cell culture scaffolds and human tissue services for drug research
REPROCELL is a life science company combining proprietary 3D cell culture products with ex vivo human tissue testing services for the pharmaceutical industry. Its scaffold enables cells to grow in three-dimensional structures that more closely replicate in vivo tissue behaviour, supporting drug safety, efficacy, and…
Automated cell culture platform and stem cell lines for biomanufacturing
Unicorn Biotechnologies is a Sheffield-based company developing automated cell culture instruments and stem cell line products for research and biomanufacturing applications. Its platform is a modular, closed-loop cell culture robot that standardises and scales cell culture workflows across drug discovery,…
Contract antibody discovery, engineering and supply services
Fusion Antibodies is a contract research organisation specialising in preclinical antibody discovery, engineering and supply for pharmaceutical and diagnostic clients. Services span antigen expression, antibody generation, humanisation, affinity maturation, developability optimisation, and stable cell line…
Research reagents, biological materials and scientific procurement support
Tebubio UK supplies research reagents, biological materials and specialist laboratory consumables to life sciences customers across the UK and Ireland. Its catalogue includes antibodies, proteins, cell culture media, primary cells, assay kits, nucleic acid tools and biochemicals from international manufacturers. The…
Specialist immunology CRO for preclinical biotherapeutic drug discovery
RoukenBio is a specialist contract research organisation providing preclinical immunology services to biopharmaceutical companies worldwide. Its team offers cell-based bioassay development, functional characterisation of antibody therapeutics and complex biologics, cell line engineering, and CMC-quality potency assay…
End-to-end viral vector design, production and gene delivery
VectorBuilder is a global provider of gene delivery solutions offering an integrated suite of research products, custom services, and clinical-grade manufacturing. The company's platform spans viral vector design and cloning, packaging of lentiviral, AAV, and adenoviral vectors, plasmid and IVT mRNA manufacture,…
Global cell and gene therapy CDMO
Minaris Advanced Therapies is a company providing contract development, manufacturing and testing services across the cell and gene therapy lifecycle. Its UK operations originate from the former Oxgene business, contributing proprietary AAV and lentiviral manufacturing technologies. In December 2025 the company…
Droplet screening technology for high-throughput biological research
AssureDrop is an early-stage UK biotech company developing droplet-based screening technology for use in drug discovery, biomarker detection, and 3D cell culture research. Its platform enables the generation and handling of droplets directly within standard multiwell plates, including 1536-well format, without the…
Quality-controlled human iPSC lines for disease modelling
EBiSC is a not-for-profit biobank supplying quality-controlled human induced pluripotent stem cell (iPSC) lines to academic and commercial researchers. Its catalogue includes disease-associated, healthy control and gene-edited isogenic cell lines for disease modelling, drug discovery and preclinical research. The…
Authenticated cell lines, cell banking and culture testing services
ECACC is the European Collection of Authenticated Cell Cultures, a UK Health Security Agency resource based at Porton Down. It preserves and supplies quality-controlled human and animal cell lines, hybridomas, induced pluripotent stem cells and nucleic acids for biomedical research. Its services include cell line…
Blood group reference testing, antibody reagents and assay development
IBGRL comprises NHS Blood and Transplant laboratories in Filton, Bristol, providing specialist blood group reference testing, transfusion research and biological reagents. Its red cell reference team investigates complex antibody and antigen cases, while IBGRL Research Products supplies monoclonal antibodies and…
Global CDMO for biologics development and manufacture
Lonza is one of the world's largest contract development and manufacturing organisations, providing services across biologics, cell and gene therapy, and small molecules. Its primary UK site in Slough is a multi-product cGMP facility specialising in mammalian biopharmaceutical development and manufacture. The…
Light-controlled droplet microfluidics for single-cell functional analysis
Lightcast Discovery is a life science tools company developing a droplet-based system for single-cell functional analysis. Using light to precisely control picolitre-scale droplets, the platform enables parallel interrogation of tens of thousands of individual cells across a range of functional assays, including…
Autonomous laboratory infrastructure for AI-ready biological data
Substrate Bio is a London biotechnology company developing AI-native automated laboratory infrastructure for biological data generation. Its platform combines robotic workcells, experimental orchestration software and structured data capture to support reproducible protein science and functional genomics workflows. It…