Drug discovery companies identify, validate and develop new therapeutic candidates for the prevention and treatment of disease. The sector combines biology, chemistry, data science and clinical expertise to bring new medicines from concept to clinic.
This category includes companies working on:
Browse 422 UK drug discovery companies below.
Small molecule remyelination therapeutics for neurological diseases
Pheno Therapeutics is a Scottish clinical-stage biotechnology company developing small molecule therapeutics that promote remyelination by boosting the function of…
Precision oncology biotech targeting novel DNA damage response pathways
Nodus Oncology is a preclinical-stage biotechnology company developing small molecule inhibitors against novel DNA damage response targets for molecularly defined cancer patient…
Antisense oligonucleotide gene therapies for rare childhood leukodystrophies
SynaptixBio is a rare disease biotech company developing gene therapies for severe leukodystrophies and childhood neurodegenerative diseases, using antisense oligonucleotide…
Long-acting eye-drop matrix technology for chronic ocular surface disease
Healome Therapeutics is a University of Birmingham spin-out developing a proprietary eye-drop matrix technology that improves drug retention, lubrication and healing on the eye…
GPCR-targeting ophthalmic therapeutics for dry eye and corneal pain
OKYO Pharma is a clinical-stage biopharmaceutical company developing treatments for inflammatory eye diseases and chronic ocular pain. Its lead candidate, urcosimod, is a…
AI-driven drug discovery targeting intrinsically disordered proteins
Peptone is a translational biophysics company developing novel therapeutics against intrinsically disordered proteins (IDPs), a class of structurally dynamic proteins implicated…
Constrained bicyclic peptide conjugates for targeted cancer therapy
Bicycle Therapeutics is a clinical-stage biopharmaceutical company developing a novel class of therapeutics based on short synthetic peptides constrained by a small molecule…
Oral microbiome therapeutics for gastrointestinal and hepatic disease
EnteroBiotix is a clinical-stage biopharmaceutical company developing orally delivered, full-spectrum microbiome therapeutics for diseases linked to gut microbiome disruption. Its…
Engineered biologics with conditional activation for precision cancer immunotherapy
Switch Biologics is a UK biotechnology company developing engineered protein biologics for cancer immunotherapy. The company applies directed evolution and protein engineering to…
GPCR-targeted small molecule therapeutics
Liminal BioSciences is a development-stage biopharmaceutical company focused on the discovery and development of small molecule therapeutics that modulate G protein-coupled…
Emergency treatment for anticoagulant-associated intracranial haemorrhage
Alveron Pharma is a clinical-stage biotechnology company developing OKL-1111, a novel drug candidate for the emergency treatment of intracranial haemorrhage and other severe…
AI-driven target identification and drug discovery from omics data
Intelligent OMICS is a biotechnology company applying artificial intelligence and machine learning to drug discovery and diagnostics. Its proprietary platform analyses…