Immunology companies study and manipulate the immune system to develop therapies, diagnostics and research tools. The field plays a central role in areas such as cancer, infectious disease, autoimmune disorders and vaccine development.
This category includes companies working on:
Browse 182 UK immunology companies below.
Automated molecular diagnostics for HLA typing and blood group testing
MC Diagnostics is a specialist molecular diagnostics company developing and manufacturing automated multiplexed assay solutions for clinical and reference laboratories. The company's proprietary platform delivers proven diagnostic assays for HLA typing and blood group testing, supported by integrated image capture and…
Single-molecule counting point-of-care diagnostics for cardiac and other biomarkers
Psyros Diagnostics develops a point-of-care diagnostic system using single-molecule counting technology to measure biomarkers at extremely low concentrations within around ten minutes, from a single drop of blood. The platform's lead application is a high-sensitivity troponin assay for cardiac diagnosis, with the…
Preclinical mRNA nanoparticle therapeutics for chronic inflammatory disease
EVolution Therapeutics is a preclinical-stage biotechnology company developing mRNA nanoparticle and hydrogel-based therapeutics to resolve chronic inflammation and support tissue repair. Spun out of Aston University, its platform delivers mRNA encoding pro-resolving proteins directly to sites of disease. The lead…
Precision cancer vaccines to prevent metastatic recurrence
Infinitopes is a clinical-stage biotechnology company developing therapeutic cancer vaccines designed to prevent metastatic recurrence. Its lead candidate ITOP1 is a precision viral vector cancer vaccine targeting tumour antigens in patients with surgically resectable oesophageal adenocarcinoma, to be administered in…
Immunometabolism-targeting small molecules for autoimmune disease
Sitryx Therapeutics is a clinical-stage biopharmaceutical company developing oral small molecule therapeutics that modulate immune cell metabolism to achieve disease remission in autoimmune and inflammatory conditions. The company's approach targets novel metabolic enzymes within immune cells, with lead programmes in…
TYK2/JAK1 inhibitor advancing towards Phase 2 psoriasis trials
Sareum is a clinical-stage biotechnology company developing small-molecule kinase inhibitors for autoimmune diseases and cancer. Its lead oral TYK2/JAK1 inhibitor, SDC-1801, completed Phase 1 testing in healthy volunteers and is being prepared for a Phase 2 study in psoriasis. Dosing in its Phase 2-enabling toxicology…
Bacterial-like particle vaccine platform targeting recurrent UTIs
Spectre Bio is a biotechnology company developing a non-antibiotic prophylactic vaccine for recurrent UTIs, a major unmet medical need and significant driver of antimicrobial resistance. The company's platform produces programmable, non-replicative bacterial cells that retain a full native antigen profile while being…
Diagnostic reagents, allergy testing products and contract diagnostics manufacturing
Bio-Diagnostics is a manufacturer of diagnostic products and provider of contract services for the in vitro diagnostics industry. Its own range covers reagents and tests for infectious disease, autoimmunity and immunohistochemistry, alongside an extensive portfolio of allergens and accessories for patch and skin prick…
Oral NLRP3 inhibitors for cardiovascular and neurologic inflammation
Rezera, formerly NodThera, is a clinical-stage biotechnology company developing small molecule inhibitors of NLRP3, an inflammasome implicated in chronic inflammatory and neurodegenerative disease. Its lead asset, ruvonoflast, is a brain-penetrant oral inhibitor that has completed Phase II trials and is advancing…
Monoclonal antibodies for viral infectious disease
RQ Biotechnology is a passive immunisation company discovering and developing long-acting monoclonal antibodies to provide immediate protection against viral infections in immunocompromised and vulnerable populations. Founded by members of the UK COVID-19 Antibody Taskforce and co-founded with LifeArc, the company's…
Topical peptide therapeutics targeting inflammatory skin disease
Carocell Bio is a pre-clinical stage biotechnology company developing proprietary peptide-based therapeutics for inflammatory diseases. Its pipeline centres on topical formulations that inhibit mitogen-activated protein kinase (MAPK/p38), a key regulator of the inflammatory cascade. Lead programmes target atopic…
Research institute studying the biology of ageing and lifelong health
The Babraham Institute is a life sciences research institute studying the biological mechanisms behind ageing, development and lifelong health. Its research spans epigenetics, immunology and cellular signalling, investigating how gene activity, the immune system and intercellular communication shape health outcomes…
Targeted magnetic blood filtration to enable gene therapies
MediSieve is a biotechnology company developing selective magnetic blood filtration using engineered particles that bind specific circulating biological targets. Its extracorporeal system combines target-specific magnetic beads with a capture device designed to remove bound substances before blood returns to the…
Immunometabolism drugs for autoimmune and inflammatory diseases
Istesso is a drug discovery and development company working in immunometabolism, developing oral small molecule therapies that reprogram cellular metabolism to treat autoimmune and inflammatory conditions. Its lead candidate is a first-in-class metabolic reprogramming agent for rheumatoid arthritis with a dual…
AI-guided personalised mRNA cancer vaccine development
Genevation is a biotechnology company developing personalised mRNA cancer vaccines using AI-assisted tumour neoantigen identification. Its platform analyses tumour sequencing data to select patient-specific targets and combines computational vaccine design with cell-free RNA manufacturing. The company reports…
In vitro pharmacology CRO for preclinical drug discovery
Excellerate Bioscience is a contract research organisation specialising in molecular and cellular pharmacology for preclinical drug discovery. The company provides in vitro assay development, biochemical and cell-based screening, target validation, and compound profiling services to pharmaceutical companies,…
GPR35 inhibitors for gastrointestinal cancer and inflammatory bowel disease
ThirtyFiveBio is a drug discovery company developing first-in-class small molecule inhibitors of GPR35, a genetically validated G protein-coupled receptor implicated in gastrointestinal disease. The company's approach targets GPR35 antagonism to prevent epithelial cell damage and dysfunction in the gut wall,…
Tissue-based endometriosis models for therapeutic target discovery
Cyclana Bio is a biotechnology company developing human tissue-based models to investigate endometriosis and identify therapeutic targets. Its research combines endometrial tissue biopsies and menstrual fluid samples with molecular profiling and three-dimensional disease models, focusing on extracellular matrix…
ELISA kits and diagnostics for research and clinical use
JR Biomedical is a North Wales-based developer, manufacturer and distributor of diagnostic reagents and ELISA kits for research institutions, NHS laboratories and pharmaceutical companies. Operating from ISO 13485-certified laboratories at the OpTIC Centre in St Asaph, the company develops human ELISA kits across…
Blood bank reagents for transfusion compatibility testing
Alba Bioscience is a manufacturer of serological reagents for immunohaematology, supplying blood banks, hospital transfusion laboratories, and national blood services worldwide. Its portfolio supports ABO and RhD blood grouping, antibody screening, and extended red cell phenotyping for manual testing workflows. The…