Explore life science companies operating throughout South East England, including biotechnology firms, CROs and research organisations.
Full-service CRO and pharmacovigilance services for biopharma
Ergomed is a global contract research organisation providing clinical development, pharmacovigilance, and regulatory compliance services to the pharmaceutical and biotechnology industries. Operating across more than 100 countries, the group manages Phase I to IV clinical trials with particular depth in oncology and…
Therapeutics to restore egg quality and improve IVF outcomes
U-Ploid Biotechnologies is an early-stage biotechnology company developing first-in-class therapeutics to address age-related decline in egg quality. Its lead programme targets chromosomal instability in human oocytes which is a primary driver of IVF failure, miscarriage, and congenital disorders in women of advanced…
Precision cancer vaccines to prevent metastatic recurrence
Infinitopes is a clinical-stage biotechnology company developing therapeutic cancer vaccines designed to prevent metastatic recurrence. Its lead candidate ITOP1 is a precision viral vector cancer vaccine targeting tumour antigens in patients with surgically resectable oesophageal adenocarcinoma, to be administered in…
Immunometabolism-targeting small molecules for autoimmune disease
Sitryx Therapeutics is a clinical-stage biopharmaceutical company developing oral small molecule therapeutics that modulate immune cell metabolism to achieve disease remission in autoimmune and inflammatory conditions. The company's approach targets novel metabolic enzymes within immune cells, with lead programmes in…
Reproductive genetic testing and embryo screening for fertility clinics
Igenomix UK is a reproductive genetics laboratory providing diagnostic testing services for fertility clinics and reproductive medicine specialists. Its services include preimplantation genetic testing for chromosomal abnormalities and inherited conditions, alongside carrier screening and endometrial assessments. The…
Platelet function biomarkers and assays for cardiovascular clinical research
HaemAnalytica is a University of Reading biotechnology spin-out developing platelet-function assays for cardiovascular research and clinical trials. Its TRIPLEcheck platform uses platelet biomarkers to predict thrombotic risk and antiplatelet treatment response. PLANA combines preserved blood samples, flow cytometry…
Bacterial-like particle vaccine platform targeting recurrent UTIs
Spectre Bio is a biotechnology company developing a non-antibiotic prophylactic vaccine for recurrent UTIs, a major unmet medical need and significant driver of antimicrobial resistance. The company's platform produces programmable, non-replicative bacterial cells that retain a full native antigen profile while being…
Mass photometry instruments for single-molecule biomolecular characterisation
Refeyn is an analytical instrumentation company and the pioneer of mass photometry, a light-scattering technique that measures the mass of individual molecules in solution without labels. Its benchtop instruments serve pharmaceutical, biotechnology, and academic customers for characterisation of proteins, nucleic…
Magdalen College's life science and technology campus in Oxford
The Oxford Science Park is a 75-acre science and technology campus on the southern edge of Oxford, owned by Magdalen College and closely linked to the University of Oxford. Home to around 100 companies employing over 3,000 people, the park is predominantly life science focused, hosting biotechnology, medical…
Blood-based microRNA test for multi-cancer early detection
Xgenera is a diagnostics company developing a blood test for the early detection of multiple cancers from a single sample. The test measures circulating microRNA biomarkers using PCR-based methods and applies machine learning to identify signals from up to 12 common cancers before symptoms appear. The company is…
Baculovirus expression systems, research reagents and contract protein production
Oxford Expression Technologies is an Oxford Brookes University and NERC spin-out specialising in recombinant protein expression. Its flashBAC baculovirus expression systems, transfer vectors and engineered insect cell lines support protein production for pharmaceutical, vaccine and diagnostic research. The company…
Generative AI and quantum chemistry platform for de novo enzyme design
Xyme is a biotechnology company developing a generative AI and quantum chemistry platform for designing novel enzymes from first principles. Its approach combines computational prediction with experimental validation to create enzymes that catalyse chemical reactions not found in nature. Applications span therapeutic…
Bacteriophage-integrated antibacterial textiles for surgical implant infection prevention
Oxford Silk Phage Technologies is a biotechnology company developing antibacterial biomaterials that integrate bacteriophages into silk-based medical textiles, for use in surgical implants and wound care devices. The technology embeds high-density cocktails of bacteriophages throughout the textile structure, producing…
AI and photonics platform for personalised drug development
iLoF is a digital health company developing an AI-powered platform that uses proprietary photonics technology to generate optical fingerprints from blood samples, building a cloud-based library of biological profiles and biomarkers. The platform enables non-invasive patient stratification and personalised drug…
Scientific laboratory informatics and chemical data management software
IDBS is a scientific informatics software company supporting laboratory workflows, experimental data capture and research data management. Its E-WorkBook Chemistry platform provides chemical structure and reaction representation, stoichiometric calculations, chemical searching and compound registration. Its wider…
Oligonucleotide therapeutics designed to upregulate protein expression
Orfonyx Bio is a biotechnology company developing genetic medicines that increase, rather than silence, the expression of therapeutic target proteins. Its platform generates antisense oligonucleotide modulators that act on regulatory elements within the untranslated regions of genes, inhibiting sequence motifs that…
Exosome-delivered gene editing therapies for neurodegenerative diseases
Evox Therapeutics is a biotechnology company developing exosome-based gene editing therapies for rare, genetically driven neurodegenerative diseases. Its proprietary platform uses engineered exosomes to deliver CRISPR-based gene editors across the blood-brain barrier, enabling targeted genetic intervention in the…
Global biopharma with major UK R&D and regulatory operations
Pfizer Limited is the principal UK subsidiary of Pfizer Inc., one of the world's largest biopharmaceutical companies. Its Sandwich, Kent site houses pharmaceutical sciences, global clinical supplies, quality assurance, and worldwide safety and regulatory operations serving over 175 markets. A Devices Centre of…
Oxford University spinout producing cultivated beef and pork
Ivy Farm Technologies is a company developing cultivated meat using a non-GMO cell culture process originally developed at the University of Oxford. Its Oxford pilot plant operates a 600-litre bioreactor with capacity to produce 2.8 tonnes of cultivated meat annually, with products including beef burgers, sausages and…
GMP/GLP contract microbiology testing for pharma and medical devices
Wickham Micro is a GMP/GLP compliant contract testing laboratory providing microbiology services to the pharmaceutical and medical device industries. Services include sterility, bioburden, bacterial endotoxin and cytotoxicity testing, microbial identification, method validation and environmental monitoring, supporting…