UK Life Sciences Company Directory

Antigen modulation therapies for cancer and autoimmune disease

Grey Wolf Therapeutics is a clinical-stage biotechnology company developing small molecule inhibitors of endoplasmic reticulum aminopeptidases (ERAP1 and ERAP2) to modulate antigen presentation on cell surfaces. In oncology, this approach enhances tumour visibility to the immune system; in autoimmunity, it aims to…

CAR T cell therapies for blood cancer and autoimmune disease

Autolus Therapeutics is a London-based commercial-stage biopharma developing next-generation programmed T cell therapies. Its lead product AUCATZYL (obecabtagene autoleucel) received FDA approval in November 2024 and MHRA conditional marketing authorisation in 2025 for relapsed or refractory B-cell acute lymphoblastic…

DNA damage response platform targeting hard-to-treat solid tumours

Artios Pharma is a clinical-stage biopharmaceutical company developing small molecule therapeutics that target DNA damage response pathways in cancer cells. The company's pipeline includes alnodesertib, an ATR inhibitor advancing toward late-stage development in ATM-deficient solid tumours, and ART6043, a DNA…

Crystal and particle engineering to improve drug performance

CrystecPharma is a pharmaceutical technology company that uses supercritical fluid processing to engineer drug crystals and particles. Its platform improves the dissolution, stability and delivery of small and large molecule medicines, including inhaled powders. The company provides formulation and process development…

UK commercial base for a rare metabolic disease biotech

Amicus Therapeutics UK is the British subsidiary of Amicus Therapeutics, a US-listed biotechnology company focused on rare metabolic diseases. The company develops enzyme replacement therapies and gene therapies targeting lysosomal storage disorders, with approved medicines for Pompe disease and Fabry disease. The UK…

Platelet function biomarkers and assays for cardiovascular clinical research

HaemAnalytica is a University of Reading biotechnology spin-out developing platelet-function assays for cardiovascular research and clinical trials. Its TRIPLEcheck platform uses platelet biomarkers to predict thrombotic risk and antiplatelet treatment response. PLANA combines preserved blood samples, flow cytometry…

DNA identification and STR-based cell-line authentication services

NorthGene is Biofortuna's genetic testing brand, operating from accredited laboratories in Deeside, Wales. Its services include DNA relationship and forensic identification testing, plus short tandem repeat profiling for cell-line authentication. Research customers can request mycoplasma detection, culture mixture…

Phase 3 urcosimod therapy for neuropathic corneal pain

OKYO Pharma is a clinical-stage biopharmaceutical company developing topical therapies for neuropathic corneal pain and other ocular surface conditions. Its lead candidate, urcosimod (formerly OK-101), is a chemerin receptor agonist designed to modulate inflammation and corneal pain signalling. Phase 2a testing…

Mass spectrometry and analytical instruments for laboratory research

LECO Instruments UK is a UK subsidiary of an international manufacturer of analytical laboratory instruments. It supplies gas chromatography, time-of-flight mass spectrometry and elemental analysis systems, with applications in metabolomics, protein analysis, pharmaceutical testing and other analytical disciplines.…

AI-native virtual scientist platform for drug discovery

Kiin Bio is a software company developing an AI-native platform that integrates virtual scientist agents with laboratory databases, modelling software and analysis tools to streamline drug discovery workflows. The platform coordinates tasks spanning literature review, experimental design, bioinformatics and…

Inhaled antifungal therapies for serious respiratory fungal infections

Pulmocide is a late-stage biopharmaceutical company developing inhaled medicines for life-threatening respiratory fungal infections. Its lead compound opelconazole is a triazole antifungal designed for inhaled delivery to maximise pulmonary drug concentration while minimising systemic exposure and drug interactions.…

First-in-class small molecule therapeutics targeting DNA uracilation in cancer

CV6 Therapeutics is a clinical-stage biotechnology company developing first-in-class small molecule drugs for cancer and inflammatory diseases. Its lead asset CV6-168 is a specific inhibitor of the enzyme dUTPase, inducing uracil misincorporation into cancer cell DNA, triggering DNA damage and immune activation.…

Cloud-based informatics platform for drug discovery data management

Collaborative Drug Discovery (CDD) is a software company providing a cloud-based informatics platform for drug discovery research. Its flagship product enables scientists to register compounds, manage bioassay and chemical data, track inventory and capture experiments through an integrated electronic laboratory…

ECM-targeted drug discovery platform for fibrosis and solid tumours

Engitix is a preclinical-stage biotechnology company developing therapeutics that target the extracellular matrix (ECM) in fibrosis and solid tumours. Its proprietary discovery platform integrates one of the largest ECM bioarchives with AI and machine learning to identify disease-specific targets and biomarkers.…

Deep learning platform for small molecule drug discovery

CHARM Therapeutics is a clinical-stage biotechnology company applying 3D deep learning to small molecule drug discovery. Its proprietary platform uses protein-ligand co-folding algorithms to predict binding interactions and identify candidates against difficult-to-drug targets. CHARM's pipeline focuses primarily on…

Engineered immune cells as living delivery vehicles for genetic medicines

Dart Biosciences is a biotechnology company developing a platform that uses engineered immune cells as living delivery vehicles for genetic medicines. By leveraging immune cells' natural ability to localise to disease-relevant tissues, the platform aims to achieve more spatially precise genetic payload transfer with…

Contract development and manufacturing of complex small molecule APIs and ADCs

Sterling Pharma Solutions is a contract development and manufacturing organisation specialising in complex small molecule active pharmaceutical ingredient development and cGMP manufacturing for the pharmaceutical and biotech industries. Capabilities include hazardous and high-potency chemistry, flow chemistry,…

Microbiome modulator ingredients for metabolic health and disease prevention

OptiBiotix Health is a biotechnology company developing and licensing microbiome modulator products for use in food ingredients, dietary supplements, and nutraceuticals. Its portfolio includes patented prebiotic and probiotic formulations targeting weight management, cholesterol reduction, cardiovascular health, and…

FDA-approved AI blood test for diabetic kidney disease risk

Renalytix is an artificial intelligence-enabled in vitro diagnostics company focused on the clinical management of chronic kidney disease. Its blood-based test combines biomarker analysis with machine learning to generate a five-year kidney function decline risk score in adults with type 2 diabetes and CKD stages 1 to…

Viral vector platform for solid tumour immunotherapy

Akamis Bio is a clinical-stage oncology company developing oncolytic adenoviral therapeutics for solid tumours. Its platform delivers immunotherapeutic payloads directly to tumour sites following intravenous dosing, enabling tumour-localised expression of proteins including CD40 agonist antibodies and cytokines. Lead…