Discover life science companies across the East of England, including biotechnology firms, CROs, research organisations and innovation hubs.
GMP compliant Cell therapy CDMO
Advent Bioservices is a contract development and manufacturing organisation specialising in cell and gene therapy, operating GMP-certified facilities at Sawston, Cambridgeshire. The company offers process development, GMP manufacturing, quality control, and ultra-cold cryogenic storage services to biotech and drug…
AI imaging platform for lung and heart disease clinical trials
Qureight is a technology-driven imaging contract research organisation providing clinical data curation and AI-powered image analysis services to pharmaceutical and biotech companies. Its proprietary platform integrates CT imaging, biomarkers, and clinical metadata from complex respiratory and cardiovascular diseases,…
Molecular biology enzymes and UK scientific reagent support
New England Biolabs (UK) is the British sales and technical-support subsidiary of New England Biolabs, supplying molecular biology reagents to research laboratories. Its catalogue includes restriction enzymes, DNA and RNA modifying enzymes, nucleic acid purification products, PCR reagents and sequencing library…
RNA-based therapeutics targeting neurodegenerative disease mechanisms
Harness Therapeutics is a Cambridge-based biotech developing oligonucleotide therapeutics that exploit post-transcriptional regulation to achieve controlled upregulation of disease-relevant proteins in the CNS. Its lead programme targets FAN1 nuclease in Huntington's disease to limit somatic DNA repeat expansion, with…
Global pharmaceutical company developing medicines across major disease areas
AstraZeneca is a multinational biopharmaceutical company engaged in the research, development, manufacture, and commercialisation of prescription medicines. Its pipeline and product portfolio span oncology, cardiovascular and metabolic disease, respiratory and immunology, rare diseases, and vaccines. The company…
Connected lab software and cell culture automation technology
Cell Culture Automation is a laboratory technology company developing software and instruments for cell culture research. Its live management platform integrates electronic notebooks, sample and inventory tracking, experimental records, equipment monitoring and budgeting. A plate-format environmental sensor monitors…
RNA trans-splicing gene therapies for aggressive cancers
Spliceor is a University of Cambridge spinout developing RNA trans-splicing gene therapies for aggressive cancers. Its platform is designed to produce therapeutic messenger RNA selectively in targeted cells by joining segments from different RNA molecules. Machine learning helps refine the constructs and optimise…
DUB inhibitor therapeutics targeting mitophagy and degenerative disease
Mission Therapeutics is a clinical-stage biotechnology company developing first-in-class small molecule inhibitors of deubiquitylating enzymes to treat diseases driven by mitochondrial dysfunction. By targeting a mitochondria-localised DUB, the company's drug candidates are designed to enhance mitophagy, the cellular…
AI-driven rescue and development of failed drug candidates
Ignota Labs is a biotechnology company that identifies, in-licenses and redevelops drug candidates that have failed clinical development due to toxicity. Using deep learning applied to cheminformatics and bioinformatics data, the company resolves the mechanistic basis of safety failures and makes targeted chemical…
Data-driven cis-bispecific antibody-drug conjugates for solid tumour cancers
Promatix Biosciences is an oncology drug discovery company developing next-generation bispecific antibody-drug conjugates through data-driven target pairing. Using a proteomics database and computational algorithms, the company identifies antigen combinations enabling selective tumour targeting, aiming to reduce…
Life sciences and technology campus south of Cambridge
Unity Campus is a life sciences and technology campus developed by Howard Group on the site of a former tannery at Pampisford, eight miles south of Cambridge, providing fully fitted laboratory and office space across a compact 11-acre site. Phase 2 expansion delivered 150,000 sq ft of new laboratory and office space…
Mitochondrial disease drug discovery subsidiary of Astellas Pharma
Astellas Engineered Small Molecules U.K. is a Cambridge-based drug discovery subsidiary of Astellas Pharma, operating as part of the company's Mitobridge Division alongside its US counterpart Mitobridge Inc. Originally founded as Nanna Therapeutics and acquired by Astellas in 2020, the entity applies a proprietary…
Handheld blood-electrolyte monitoring technology for kidney and cardiovascular care
Kalium Health is a medical technology company developing handheld blood-electrolyte monitoring for people with kidney and cardiovascular conditions. Its device is designed to measure potassium and other electrolytes from a single drop of blood using disposable test consumables, supporting monitoring outside…
CDMO supplying custom reagents, antibodies, and diagnostic components
Life Science Group is an independent UK contract development and manufacturing organisation supplying custom cell culture media, sera, buffers, and reagents, alongside antibody generation services and diagnostic kit components. Operating from an ISO 9001 and ISO 13485 certified facility in Bedfordshire, the company…
Novel methylation amplification platform for clinical genomic diagnostics
Syndex Bio is a Cambridge-based biotechnology company developing a proprietary platform technology that enables amplification of DNA methylation for the first time. Unlike conventional PCR, which cannot preserve 5-methylcytosine signals, mcPCR copies both the four-base DNA code and its methylation patterns from…
Clinical-stage biotech developing treatments for multiple myeloma
CellCentric is a clinical-stage biopharmaceutical company developing inobrodib, a first-in-class oral inhibitor of the p300/CBP transcription co-activation proteins, for relapsed and refractory multiple myeloma. Inobrodib has been evaluated in over 400 patients and holds FDA Fast Track and orphan drug designations.…
Immuno-oncology therapies targeting the nfP2X7 cancer receptor
Biosceptre is a UK-headquartered clinical-stage biotechnology company developing cancer therapeutics based on its proprietary nfP2X7 platform. The nfP2X7 receptor is a non-functional form of P2X7 expressed on cancer cells across a broad range of tumour types, enabling targeted therapeutic approaches. The pipeline…
Precision small molecule drugs for obsessive-compulsive disorder
Serenatis Bio is a preclinical-stage biotech developing small molecule drugs to treat obsessive-compulsive disorder (OCD). Its pipeline of three candidates targets distinct neurological mechanisms, including glutamate, AMPA, and dopamine pathways, with a biomarker-driven approach designed to match patients to…
Portable PCR diagnostics for high-consequence infectious diseases
BioGene develops portable real-time PCR instruments and diagnostic reagents for detecting infectious pathogens. Its extraction-free, freeze-dried chemistry is designed to detect pathogens directly from crude samples in under 30 minutes, reducing the need for conventional laboratory preparation. The company's assays…
Research reagents, biological materials and scientific procurement support
Tebubio UK supplies research reagents, biological materials and specialist laboratory consumables to life sciences customers across the UK and Ireland. Its catalogue includes antibodies, proteins, cell culture media, primary cells, assay kits, nucleic acid tools and biochemicals from international manufacturers. The…