UK Life Sciences Company Directory

Industrial biotechnology research translation and commercialisation support

Industrial Biotechnology Innovation Catalyst is an EPSRC-funded programme helping universities and companies translate industrial biotechnology research into commercial applications. Led by the University of Manchester with north-west academic and industry partners, it provides funding for proof-of-concept projects,…

Ex vivo haematopoietic stem cell gene therapies for rare genetic diseases

Orchard Therapeutics is a gene therapy company developing ex vivo haematopoietic stem cell therapies for rare genetic diseases, primarily severe neurometabolic and immunological disorders in children. Its platform modifies a patient's own stem cells with a functional copy of the defective gene before reinfusion. Lead…

Therapeutics to restore egg quality and improve IVF outcomes

U-Ploid Biotechnologies is an early-stage biotechnology company developing first-in-class therapeutics to address age-related decline in egg quality. Its lead programme targets chromosomal instability in human oocytes which is a primary driver of IVF failure, miscarriage, and congenital disorders in women of advanced…

Precision calcium channel medicines for epilepsy and Parkinson's disease

Lario Therapeutics is developing first-in-class precision medicines as disease-modifying treatments for severe neurological disorders, including genetically defined epileptic encephalopathies and Parkinson's disease. The company's pipeline centres on neuronal calcium channel inhibitors, beginning with genetically…

RNA-targeted drug discovery platform using machine learning

RevoNA Bio is a biotechnology company developing a high-throughput RNA biological platform for RNA-targeted drug discovery. The platform generates comprehensive RNA structural and functional datasets that feed a machine learning predictive engine, supporting hit identification, structure-activity relationship…

Anti-virulence drug discovery from natural bioactive compounds

Neem Biotech is a Wales-based drug discovery company developing novel non-traditional antimicrobial treatments derived from naturally inspired compounds. The company specialises in quorum sensing inhibitors and anti-biofilm agents, with programmes targeting wound infection and cystic fibrosis. Its discovery approach…

Ion channel drug discovery platform for rare CNS disorders

Autifony Therapeutics is a clinical-stage UK biotech developing small molecule modulators of Kv3 voltage-gated potassium channels for rare genetic CNS disorders. Lead programmes target Fragile X syndrome and rare myoclonic epilepsy syndromes, with preclinical work extending to schizophrenia, hearing loss, and…

Clinical whole genome sequencing and reporting platform

StoreGene is a UCL spin-out providing a clinical genomic operating system that integrates whole genome sequencing with automated bioinformatics pipelines and genomic counselling services. Its platform generates clinical reports across cardiovascular genetics, hereditary cancer, pharmacogenomics, and nutrigenetics,…

Carbon capture and biomanufacturing using engineered cyanobacteria

CyanoCapture is a company developing a biomanufacturing platform that uses genetically engineered cyanobacteria to sequester carbon dioxide and convert it into high-value products including recombinant proteins and graphite. Its photobioreactor-based system is designed to offer affordable carbon capture for industrial…

Pharmacovigilance consultancy for clinical and post-marketing drug safety

Drive Phase PV Limited is a UK pharmacovigilance consultancy providing drug safety and device-vigilance services across clinical development and post-marketing settings. Services include PV system design, safety database management, signal detection, risk management plans, QPPV provision, periodic safety reporting,…

Pheromone-based insect monitoring and biorational pest management products

Russell IPM is a UK manufacturer of pheromone-based insect monitoring and control systems, biorational pesticides, and biological crop protection products for agriculture, horticulture, stored products, and public health applications. Operating through subsidiaries covering pheromone lures, microbial fermentation…

Fibroblast immunology platform targeting cancer and inflammatory disease

Mestag Therapeutics is a clinical-stage biotechnology company developing first-in-class antibody therapies that target activated fibroblasts to modulate immune responses in cancer and inflammatory disease. Its lead programme, MST-0312, is a FAP-targeted LTBR agonist bispecific antibody designed to induce tertiary…

AI-driven mass spectrometry biomarker services for diagnostics and drug development

Guilford Street Laboratories Ltd is a contract research organisation providing machine learning-powered mass spectrometry services for biomarker discovery, assay development, and precision medicine. The company specialises in high-sensitivity multi-omic analysis of protein, lipid, and metabolite biomarkers, supporting…

UK trade association for in vitro diagnostics manufacturers and distributors

The British In Vitro Diagnostics Association (BIVDA) is the national trade body for the UK IVD industry, representing over 200 manufacturers and distributors of in vitro diagnostic products. BIVDA advocates on behalf of its members to government, the NHS and professional bodies, and engages with international…

Human iPSC-derived disease models and drug discovery services

Axol Bioscience is a biotechnology company supplying human induced pluripotent stem cell-derived cells and research services for disease modelling and drug discovery. Its portfolio includes neurons, cardiomyocytes, retinal organoids, retinal pigment epithelium and skin cell models, alongside culture media and custom…

RNA trans-splicing gene therapies for aggressive cancers

Spliceor is a University of Cambridge spinout developing RNA trans-splicing gene therapies for aggressive cancers. Its platform is designed to produce therapeutic messenger RNA selectively in targeted cells by joining segments from different RNA molecules. Machine learning helps refine the constructs and optimise…

Synthetic VHH antibody libraries and discovery services

Isogenica is a contract discovery company specialising in VHH single-domain antibody discovery, offering what it describes as the world's largest synthetic VHH library alongside its proprietary screening platform. The company partners with pharmaceutical and biotechnology companies to identify high-affinity antibody…

Small molecule protein degraders targeting oncology and CNS disease

Kesmalea Therapeutics is a biotechnology company developing oral small molecule therapeutics that modulate protein homeostasis through targeted protein degradation and stabilisation. The company's platform is designed to convert the potency of protein degrader approaches into orally bioavailable, CNS-penetrant small…

One-step encapsulation drug delivery platform for advanced therapeutics

PNAS Therapeutics is a UK-based drug delivery company developing a one-step encapsulation platform designed to simplify complex pharmaceutical manufacturing processes. The platform enhances local delivery through improved bioavailability and targeting, is compatible with multiple active pharmaceutical ingredients, and…

World's oldest agricultural research institute studying sustainable farming systems

Rothamsted Research is an agricultural research institute studying crops, soils and sustainable farming systems from gene to field. The institute's work spans crop genetics, gene editing, entomology and agri environmental science, supported by bioscience techniques including proteomics, metabolomics and automated…