Biotechnology companies apply biological science to develop products, services and technologies that address challenges in healthcare, agriculture, industry and environmental sustainability.
This category includes companies working on:
Browse 360 UK biotechnology companies below.
Year-long subcutaneous drug-releasing implants for chronic disease management
imphatec is a drug delivery company developing subcutaneous implants that release medicines steadily for up to a year, with the aim of replacing daily tablets for people managing chronic and long-term conditions. Its implants are formulated to deliver a customised daily dose of a drug from a polymer matrix placed…
Cell profiling and precision additives for biologic manufacturing
Silvia Bio is a University of Sheffield spin-out developing cell-profiling services and media additives for mammalian-cell biomanufacturing. Its platform identifies cellular bottlenecks limiting productivity and biologic product quality, then formulates bioreactor-compatible additives to address them without genetic…
Cancer genetics testing and contract research
Oncologica provides molecular cancer diagnostics and contract research services from its laboratory at Chesterford Research Park near Cambridge. Its Oncofocus testing uses tumour DNA profiling to help clinicians identify potentially relevant targeted treatments and immunotherapies. The company also develops…
Targeted lipid nanoparticle delivery platform for precision therapeutics
Hone Bio is a preclinical biotechnology company developing targeted lipid nanoparticle drug delivery technology. Its proprietary platform uses engineered proteins that enable cell-specific LNP delivery while actively blocking off-target liver uptake, addressing a key limitation of conventional LNP systems. The…
Targeted protein degradation platform for neurodegenerative disease
TRIMTECH Therapeutics is a biotechnology company developing small-molecule degraders that selectively remove disease-causing protein aggregates while preserving the functional, non-aggregated forms of the same proteins. The platform is built on research into the E3 ubiquitin ligase TRIM21, conducted over nearly two…
Rapid diagnostic platforms for infectious disease and consumer testing
Sapphiros is a privately held diagnostics portfolio company backed by KKR and Neoenta. UK operations include Biocrucible, a molecular diagnostics company developing ultra-rapid isothermal nucleic acid amplification assays, and an Extreme Volume Manufacturing capability producing lateral flow diagnostic tests at…
AI-designed antibody biologics adapting human therapeutics for companion animals
Antigenesis Biologics is a biotechnology company developing targeted biological treatments for companion animals, applying expertise in human antibody therapeutics to address a gap between human and veterinary healthcare innovation. The company uses AI and computational design approaches to develop antibody-based…
RBC derived nanoparticles for RNA delivery to brain and immune cells
Crane Biosciences is a biotechnology company developing a non-immunogenic RNA delivery platform based on nanoparticles derived from red blood cell membranes. By using the body's own cellular architecture as a delivery vehicle, the platform achieves substantially higher in vivo delivery efficiency to target tissues…
Microfluidic 3D disease models for preclinical drug screening
ScreenIn3D is a biotechnology company and contract research organisation providing drug screening using three-dimensional human cell and tissue models. Its microfluidic platform supports tumour spheroids, organoids and co-cultures, enabling researchers to assess candidate efficacy, toxicity and drug combinations from…
Tunable covalent chemistry platform for neurodegenerative disease
Dunad Therapeutics is a drug discovery biotech developing small molecule therapies for neurodegenerative diseases including ALS, frontotemporal dementia, and Parkinson's disease. Its platform combines tunable covalent chemistry with targeted protein degradation, using monovalent small molecules that form durable bonds…
Stem cell-derived exosome platform for targeted drug delivery
ReNeuron is a biotechnology company developing a stem cell-derived exosome platform for targeted therapeutic delivery. Founded on over two decades of stem cell science, including the world's first clinical trial of conditionally immortalised neural stem cell therapy for stroke disability, the company has pivoted to…
Rapid bacterial viability detection using optical electrophysiology
Cytecom is a biotechnology company developing instruments for the rapid detection and quantification of live bacteria. The company's platform combines fluorescence microscopy with electrical stimulation to assess bacterial membrane potential, distinguishing viable from non-viable cells within minutes. The technology…
Semiconductor biosensors for blood-based cancer biomarker detection
ExoNostic is a diagnostic technology company developing semiconductor biosensors for cancer biomarker detection. Its investigational lab-on-a-chip platform is designed to identify molecular signatures in small blood samples, combining sensor-based measurements with computational interpretation. An Innovate UK-funded…
Pre-cancer intervention to prevent cancer before it develops
Omos Biosciences is an early-stage biotechnology company developing approaches to cancer prevention through intervention at the pre-cancerous stage, rather than treatment of established disease. The company's strategy builds on established precedents in early cancer prevention, such as polyp removal to prevent…
Phage-based blood test for tuberculosis and mycobacterial disease
PBD Biotech is a diagnostics company that develops phage-based blood and milk tests for detecting active mycobacterial infections, including bovine tuberculosis, Johne's disease and human tuberculosis. Its proprietary technology uses bacteriophages to selectively infect live mycobacteria, enabling rapid, accurate…
Electrospun biomimetic scaffold platform for wound repair
Corryn Biotechnologies is a Welsh biotechnology company developing an electrospinning platform that fabricates nano- and microfibrous polymer scaffolds directly onto wound sites at the point of care. The resorbable scaffolds mimic the architecture of the extracellular matrix, supporting tissue regeneration in chronic…
In vivo cell reprogramming therapies for degenerative disease
Mogrify is a biotechnology company developing a novel class of in vivo reprogramming therapies for degenerative diseases. Its proprietary platforms use large-scale transcriptomic and epigenomic network data to predict the transcription factors required to convert mature human cells directly into target therapeutic…
Cell rejuvenation to reverse disease and age-related disability
Altos Labs studies cellular rejuvenation, aiming to restore cell resilience and understand biological processes underlying disease, injury and ageing. Its international research institutes combine experimental biology, computational science and therapeutic development. Research includes cellular reprogramming and…
Cell-free DNA capture reagents for liquid biopsy and cancer diagnostics
BIOCAPTIVA is a biotechnology company developing novel cell-free DNA capture technology to improve liquid biopsy for cancer research and diagnostics. Its proprietary polymer platform captures cfDNA directly from whole blood without centrifuges or additional reagents, delivering substantially higher cfDNA yields than…
Next-generation targeted protein degradation therapeutics
Amphista Therapeutics is a Cambridge-based biopharmaceutical company developing next-generation targeted protein degradation medicines. Its proprietary platform generates bifunctional small molecule degraders that harness a broader range of the cell's protein-degrading machinery than existing approaches, enabling…