Small molecule drug companies develop low-molecular-weight medicines designed to interact with specific biological targets. These compounds can often enter cells and may be formulated as oral or other conventional dosage forms across a wide range of therapeutic areas.
This category includes companies working on:
Browse 202 UK small molecule drug companies below.
Galectin-3 targeted small molecule therapeutics for cancer and fibrosis
Galytx is a University of Liverpool spin-out developing small molecule therapeutic drugs that target galectin-3, a protein closely associated with cancer, fibrosis and…
Precision oncology biotech targeting synthetic lethality in cancer
Tessellate Bio is a precision oncology company developing small molecule drugs that exploit synthetic lethality, the principle that certain genetic vulnerabilities in cancer cells…
Integrated drug discovery CRO from target to clinical candidate
Sygnature Discovery is a UK-headquartered integrated drug discovery contract research organisation. Operating from sites in Nottingham, Alderley Park, and Glasgow, the company…
AI drug discovery platform targeting neurological diseases
CoSyne Therapeutics is a drug discovery company applying AI and computational methods to identify and develop therapeutics for neurological diseases. The company describes its…
Global drug discovery and development partnership company
Evotec is a global drug discovery and development company with major UK operations at Milton Park, Abingdon, and Alderley Park, Cheshire. Its Abingdon campus houses over 800 staff…
In silico software and AI for small molecule drug discovery
Optibrium is a software company providing integrated computational platforms for small molecule design, optimisation and data analysis across preclinical drug discovery. Its tools…
AI and quantum-chemical platform for small-molecule drug design
Tres Alchemix is the UK subsidiary of a Japanese biotechnology company developing an AI-driven drug-design platform for small-molecule therapeutics. The platform integrates…
ACE inhibitors for safer cardiovascular and fibrosis treatment
Angiodesign is a seed-stage drug discovery company developing next-generation domain-selective inhibitors of angiotensin-converting enzyme (ACE). Unlike current-generation ACE…
Chemistry-led CRO and CDMO for pharmaceutical and diagnostics R&D
High Force Research is an independent chemistry CRO and CDMO providing synthetic chemistry, process development, and GMP manufacturing services to the pharmaceutical, biotech, and…
Integrated academic drug discovery facility for anti-infectives and innovative targets
The Drug Discovery Unit is an academic drug discovery facility at the University of Dundee, integrating medicinal chemistry, high-throughput screening, structural biology, cell…
CBD-based licensed medicines for chronic inflammatory pain
Ananda Pharma is an AQSE-listed UK biotechnology company developing pharmaceutical-grade cannabidiol formulations as licensed medicines for chronic inflammatory pain conditions.…
Inhaled antifungal therapies for serious respiratory fungal infections
Pulmocide is a late-stage biopharmaceutical company developing inhaled medicines for life-threatening respiratory fungal infections. Its lead compound opelconazole is a triazole…