Discover life science companies across the East of England, including biotechnology firms, CROs, research organisations and innovation hubs.
Non-invasive vaginal sampling for gynaecological disease
Ellele Health is a medical research company developing a minimally invasive vaginal sampling device and associated downstream assays for the detection and management of gynaecological conditions. Using a proprietary biospecimen collected from the vaginal wall, the company applies genetic, epigenomic, and microbial…
GMP-grade cell-free synthetic DNA for genetic medicines
4basebio is a biotechnology manufacturing company producing GMP-grade synthetic DNA for use in cell and gene therapies, mRNA vaccines and genome editing applications. Using an enzymatic, cell-free synthesis process, the company manufactures application-specific linear DNA constructs that overcome the purity and…
Human ovarian cell models and multi-omics drug discovery
OvartiX is a Cambridge biotechnology company developing drug-discovery tools and therapeutic programmes for ovarian and reproductive health. Its platform combines human multi-omics datasets, machine learning and engineered two- and three-dimensional ovarian cell models to identify and validate disease targets. Founded…
Single-cell somatic mutation analysis for measuring biological ageing
AgeCurve is a geroscience company developing diagnostics that measure biological ageing at the level of individual cells. Its approach analyses the burden and lineage structure of somatic mutations in single cells, combining genotype with cellular phenotype data through machine learning to estimate how far ageing has…
In silico software and AI for small molecule drug discovery
Optibrium is a software company providing integrated computational platforms for small molecule design, optimisation and data analysis across preclinical drug discovery. Its tools support compound property prediction, multi-parameter optimisation, AI-driven data analysis, de novo design, and structure-based modelling,…
Nanoparticle platform for targeted genetic medicine delivery
ViaNautis is a nanomedicine company developing a polymer nanoparticle platform for the targeted intracellular delivery of genetic therapeutic payloads across difficult-to-penetrate biological barriers. The platform is designed to encapsulate a broad range of genetic cargoes and guide them to specific tissues and cell…
Bispecific antibody platform for cancer immunotherapies
F-star Therapeutics is a clinical-stage biotechnology company developing tetravalent bispecific antibodies for cancer and other serious diseases. Its proprietary platform creates antibodies with four binding sites that simultaneously target two different antigens, enabling focused immune activation in the tumour…
Research collaboration and seed funding for engineering biology
Engineering Biology Interdisciplinary Research Centre is a University of Cambridge initiative supporting research and collaboration in synthetic and engineering biology. It connects academic groups, students and industrial partners across molecular engineering, biomaterials, instrumentation and responsible…
Cheminformatics software for chemical search and drug discovery
NextMove Software is a scientific software company developing cheminformatics tools for pharmaceutical, chemical and biotechnology research. Its applications search molecular structures, extract chemical names and reactions from patents, and analyse electronic laboratory notebook records. The company also supplies…
Rapid molecular tests for industrial and bioprocess contamination
Fuse Diagnostics develops rapid, low-cost molecular tests for use at the point of need. Its disposable tests use proprietary amplification chemistry to detect pathogens and contaminants in under ten minutes, without requiring specialist laboratory infrastructure. The company targets applications in bioprocessing, cell…
Pre-competitive biologics drug discovery platforms and services for partners
Alloy Therapeutics UK is the Cambridge-based research operation of Alloy Therapeutics, a biotechnology platform company providing pre-competitive drug discovery technologies and services across antibody, TCR, genetic medicine, cell therapy, peptide, and drug delivery modalities. The company offers both discovery…
OrganoMaps AI and multi-omics modelling for drug discovery
AI VIVO is a Cambridge biotechnology company combining machine learning and multi-omics data to model disease biology and drug responses. Its OrganoMaps approach links molecular measurements with tissue and organ-level physiological networks, supporting analysis of therapeutic targets and mechanisms of action. The…
Organ-on-a-chip systems for human-relevant preclinical drug testing
CN Bio is a UK biotechnology company developing organ-on-a-chip microphysiological systems for preclinical drug discovery and safety testing. Its platform recreates human organ microarchitecture using primary cells and microfluidic perfusion, enabling researchers to generate human-relevant efficacy, metabolism and…
Systemic viral immunotherapy for solid tumours
Stratosvir develops engineered viral immunotherapies for advanced solid tumours and their metastases. Its platform aims to overcome the limitations of injecting therapeutic viruses directly into tumours by enabling systemic, intravenous delivery. Within tumour tissue, the viruses are designed to replicate selectively…
University research institute advancing stem cell biology and therapeutics
Cambridge Stem Cell Institute is a University of Cambridge research institute investigating stem cell biology, tissue maintenance and disease. Its research groups study stem cell states, disease mechanisms and therapeutic applications using cell culture, genomics, imaging and experimental models. Based at Cambridge…
Precision-programmed human iPSC-derived cells for biomedical research
bit.bio is a Cambridge-based synthetic biology company that programmes human induced pluripotent stem cells into defined, mature cell types for use in pharmaceutical and academic research. Its precision cell programming technology produces consistent, characterised human cells at industrial scale, supporting drug…
Platform for controlled, repeatable cellular rejuvenation therapeutics
BioRes is a preclinical biotechnology company developing a platform for controlled, repeatable cellular rejuvenation. The company's approach aims to restore cellular function as a way of addressing the underlying biological causes of age-related decline and disease, rather than treating individual conditions in…
University algal cultivation and pilot-scale research facility
Algal Innovation Centre is a University of Cambridge research facility supporting laboratory and pilot-scale cultivation of microalgae. Based at the Department of Plant Sciences, its 164-square-metre research glasshouse offers photobioreactors, algal growth monitoring and harvesting equipment. Facilities support…
Rejuvenation biology company decoding the genomics of cellular ageing reversal
clock.health is a biotechnology company developing therapies to reverse cellular ageing and extend healthspan by decoding the biological programmes that govern cell rejuvenation. Using a proprietary model in which human induced pluripotent stem cells are artificially aged then permitted to self-rejuvenate, the company…
Antibody therapeutics targeting glycosphingolipid inflammation
Protalea Bio is a biotech company developing first-in-class therapeutic antibodies to prevent progression from precancerous states to active blood cancers including multiple myeloma and B-cell lymphoma. The company's approach targets glycosphingolipid-related inflammation before disease onset, building on over fifteen…